<i>KIF3A</i> SNP associations with asthma.

a<p>The discovery Caucasian population and African American population consisted of asthmatic children from the GCPCR and non-asthmatic/non-allergic controls from the GCPCR and GCC. Associations between asthmatics and controls were tested using an additive model. Odds ratios (OR) were determined using logistic regression based on the minor allele after adjusting for age, gender and population stratification. Bolding indicates the SNP associations <0.05. 7 of 9 SNPs were significant even after considering multiple comparisons (p<0.0006).</p>b<p>The Secondary Caucasian population consisted of asthmatic children from the GCC and non-asthmatic adult controls from the CCC. OR and p-values were determined using HapMap CEU results (release 22) and Affymetrix data from each cohort for imputation analysis.</p>c<p>The Puerto Rican and Mexican populations consisted of mother, father, child trios enrolled in the GALA Study. The value provided is the frequency of childhood asthmatics within those trios.</p>d<p>Major and minor alleles are reversed in African Americans;</p>e<p>Value of fixation index (F_ST) between CHB (China/Beijing) and CEU (Caucasian Europe, as represented by Utah) HapMap populations.