Survival of mice after intranasal inoculation with <i>S. pneumoniae</i>.
- Shirin Elhaik-Goldman (345686)
- Daniel Kafka (345688)
- Rami Yossef (232981)
- Uzi Hadad (345691)
- Moshe Elkabets (345694)
- Alexandra Vallon-Eberhard (345697)
- Luai Hulihel (345700)
- Steffen Jung (192792)
- Hormas Ghadially (345703)
- Alex Braiman (345705)
- Ron N. Apte (102550)
- Ofer Mandelboim (23173)
- Ron Dagan (57723)
- Yaffa Mizrachi-Nebenzahl (345706)
- Angel Porgador (23172)
Publication date
February 2013
DOIAbstract
<p>(A) <i>Ncr1</i><sup>+/+</sup> (WT, n = 13), <i>Ncr1</i><sup>+/gfp</sup> (Het, n = 6) and <i>Ncr1</i><sup>gfp/gfp</sup> (KO, n = 12) C57BL/6 mice were challenged intranasally with high lethal dose of <i>S. pneumoniae</i> strain WU2 in 25 µl PBS. Survival was monitored daily for 8 days. Results are the summary of two independent experiments. Statistical analysis revealed significant differences in survival rates between <i>Ncr1</i><sup>+/+</sup> and <i>Ncr1</i><sup>gfp/gfp</sup> mice, while <i>Ncr1</i><sup>+/+</sup> mice had higher survivel rate (*p<0.05, two-tailed Mann-Withney U-test, line is for geometric mean).</p
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