Analysis of individual gait parameters over time in SOD1^G93A transgenic mice.

<p>Selected gait parameters from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023244#pone-0023244-t003" target="_blank">table 3</a> were subjected to two-way ANOVA with Bonferroni post-tests. Average stand time (a) in seconds, hindlimb stride length (b) in mm, use of diagonal support (% of time) and use of three limbs for support (% of time) +/− standard deviation for SOD1^G93A mice versus non-transgenic (NTG) control mice at weekly intervals between 35 and 105 days of age are shown. Asterisks indicate p<0.05 (*), p<0.01 (**) and p<0.001 (***) using bonferroni post test following two-way ANOVA on raw data (a, b) or logit transformed data (c, d). The majority of differences were detectable post-onset of classical signs (∼75 days).