PAX2 is expressed in melanocytes of benign nevi and melanoma cells of patients with malignant melanoma.

<p>Tissue sections of benign nevi (<b>A</b>) and malignant melanoma (<b>B</b>) were investigated by double immunofluorescence analysis with S100 (melanocyte marker) and PAX2 specific antibodies. S100 expression was visualized by Cy3 coupled secondary antibodies (red) and PAX2 expression was detected with Alexa488 coupled goat anti-rabbit secondary antibodies (green). White arrows in the higher magnified insets indicate PAX2 expression in nucleoli of melanocytes of benign nevi (<b>A</b>), yellow arrows in the higher magnified insets specify PAX2 expression in nucleoli of melanoma cells (<b>B</b>).