Expression of nuclear-coded genes related to metastasis in the isolated transmitochondrial cybrids.

<p>Normal mtDNA from fetal fibroblasts was transferred into ρ⁰ MDA-MB-231 cells, and its effects on the expression of the nuclear-coded genes related to metastasis were examined using real-time PCR analysis (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0023401#s2" target="_blank">Materials and Methods</a>). Bars represent the mean ± S.D. (<i>n</i> = 3).