<p>Vector genome copy numbers in various tissues were quantified by quantitative real-time PCR using CMV-promoter-specific primers. Tissues were harvested 28 days after intravenous injection of capsid-modified or wild type vectors, respectively. Recovered vector genome numbers are shown for <b>A</b> liver, <b>B</b> cardiac, and <b>C</b> lung tissue. (n = 3 animals per group).</p
International audienceLegitimate uses of gene transfer technology can benefit from sensitive detecti...
<p>The presence of viral genomic RNA was determined by RT-PCR analysis in whole blood (A) and in pla...
<p>(<b>a</b>) Schematic outline of the viral vector constructs and location of real-time PCR primers...
<p>Liver genomic DNA was analyzed by quantitative real-time PCR using primers and probe detecting th...
<p>(A) To determine viral distribution within the primary target tissues, genomic DNA (gDNA) was iso...
<p>Mice were euthanized 2 months after i.v. injection of AAV-VIP vector with mutated BChE at a dose ...
<p>Ad5(GFP), Ad5PTD(GFP), Ad5f35(GFP) and Ad5PTDf35(GFP) virus vectors (evg = 5×10<sup>9</sup>) were...
<p>(A) Viral copy number in different organs after injecting AdEasy into the liver. (B) Viral copy n...
International audienceLentiviral vectors are effective tools for gene transfer and integrate variabl...
<p><b>A)</b> SIV DNA copies in samples from the livers of both infant and adult macaques were determ...
<p>Detection and quantification of viral DNA loads in lymphoid tissues, as well as spleen and lung, ...
This study investigated the bio-distribution and persistence of plasmid DNA following intramuscular ...
<p>A SYBR-green assay and plasmid standard was used for the CAV and CPV samples, whilst the HCV and ...
<p>C57Bl/6 female mice were injected intravenously with PBS, 50 ng RT of LV-VSVg or LV-MHCII. 3 days...
<p>1 µg of CELiD DNA or 10 µg of the circular plasmid DNA was administrated by hydrodynamic tail vei...
International audienceLegitimate uses of gene transfer technology can benefit from sensitive detecti...
<p>The presence of viral genomic RNA was determined by RT-PCR analysis in whole blood (A) and in pla...
<p>(<b>a</b>) Schematic outline of the viral vector constructs and location of real-time PCR primers...
<p>Liver genomic DNA was analyzed by quantitative real-time PCR using primers and probe detecting th...
<p>(A) To determine viral distribution within the primary target tissues, genomic DNA (gDNA) was iso...
<p>Mice were euthanized 2 months after i.v. injection of AAV-VIP vector with mutated BChE at a dose ...
<p>Ad5(GFP), Ad5PTD(GFP), Ad5f35(GFP) and Ad5PTDf35(GFP) virus vectors (evg = 5×10<sup>9</sup>) were...
<p>(A) Viral copy number in different organs after injecting AdEasy into the liver. (B) Viral copy n...
International audienceLentiviral vectors are effective tools for gene transfer and integrate variabl...
<p><b>A)</b> SIV DNA copies in samples from the livers of both infant and adult macaques were determ...
<p>Detection and quantification of viral DNA loads in lymphoid tissues, as well as spleen and lung, ...
This study investigated the bio-distribution and persistence of plasmid DNA following intramuscular ...
<p>A SYBR-green assay and plasmid standard was used for the CAV and CPV samples, whilst the HCV and ...
<p>C57Bl/6 female mice were injected intravenously with PBS, 50 ng RT of LV-VSVg or LV-MHCII. 3 days...
<p>1 µg of CELiD DNA or 10 µg of the circular plasmid DNA was administrated by hydrodynamic tail vei...
International audienceLegitimate uses of gene transfer technology can benefit from sensitive detecti...
<p>The presence of viral genomic RNA was determined by RT-PCR analysis in whole blood (A) and in pla...
<p>(<b>a</b>) Schematic outline of the viral vector constructs and location of real-time PCR primers...