Differences of RNFLT between SCA1 and HC.

<p>(A) Average RNFLT (in µm) of the total ring scan (G) and in the different sectors (nasal-superior (NS), nasal (N), nasal-inferior (NI), temporal-inferior (TI), temporal (T) and temporal-superior (TS)). Error bars indicate standard deviation. Significance levels (*** for p<0.001, ** for p<0.01 and * for p<0.05) were calculated by GEE. (B) Mean RNFLT profile of both study groups in µm. (C) Both eyes (OD = right, OS = left) of a sample patient (upper line) with typical RNFLT sectors in comparison with matched healthy control (bottom line). The colors of the sectors are related to the comparison with the Spectralis normative database. Green indicates thickness values within the 95%-percentile of the database, while sectors in yellow were thinner than the 5%-percentile of the normative database and sectors in red were within the lowest 1%.