<p>The 23 samples were from a cohort of 311 participants. The heat map shows samples represented in rows and assigned numerical patient identifiers and testing methodologies in columns. Three colors are used to indicate the results: red, resistant; green, sensitive; yellow, not done, negative for <i>M.tb</i>, contaminated, or inconclusive. The samples are sorted into AFB-negative or -positive, with RIF and INH profiles in blocks side by side. Two columns are shown for the RIF results generated from the Xpert MTB/RIF using the amplification cycle threshold maximums 3.5 and 5.0. MDR TB was identified in two patients.</p
<p>RIF = Rifampicin</p><p>INH = Isoniazid</p><p>RIF<sup>R</sup> INH<sup>R</sup> = MDR-TB.</p><p>RIF<...
<div><p>Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and...
Item does not contain fulltextOBJECTIVES: Treatment outcome of MDR-TB is critically dependent on the...
<p>Fold changes are relative to the average abundance in the TST<sup>–</sup> group. Red indicates re...
We performed the first studies of analytic sensitivity, analytic specificity, and dynamic range for ...
<p>Diagram showing the detection of non-MDR-TB and MDR-TB. Individuals with MDR-TB transition throug...
<p>DZN = Direct Zielh Neelsen, DFM = Direct Fluorescent Microscopy, CFM = Concentrated Fluores...
Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and managem...
<p>The metric used to cluster this data is based on the t-statistic generated from the Student’s t-t...
<p>Legend: *According to WHO criteria [<a href="http://www.plosone.org/article/info:doi/10.1371/jour...
MTB/RIF (Xpert) enabled simultaneous screening for tuberculosis (TB) and drug susceptibility in all...
<p>The sequence of diagnostic tests in each algorithm and the action taken based on test results is ...
The global burden of tuberculosis (TB), particularly with multidrug resistance (MDR), is escalating ...
In this pilot study, we evaluated the Xpert® MTB/RIF assay in an active case-finding strategy, using...
<p>Abbreviations: CI, confidence interval; MGIT, Mycobacteria Growth Indicator Tube; PPV, positive p...
<p>RIF = Rifampicin</p><p>INH = Isoniazid</p><p>RIF<sup>R</sup> INH<sup>R</sup> = MDR-TB.</p><p>RIF<...
<div><p>Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and...
Item does not contain fulltextOBJECTIVES: Treatment outcome of MDR-TB is critically dependent on the...
<p>Fold changes are relative to the average abundance in the TST<sup>–</sup> group. Red indicates re...
We performed the first studies of analytic sensitivity, analytic specificity, and dynamic range for ...
<p>Diagram showing the detection of non-MDR-TB and MDR-TB. Individuals with MDR-TB transition throug...
<p>DZN = Direct Zielh Neelsen, DFM = Direct Fluorescent Microscopy, CFM = Concentrated Fluores...
Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and managem...
<p>The metric used to cluster this data is based on the t-statistic generated from the Student’s t-t...
<p>Legend: *According to WHO criteria [<a href="http://www.plosone.org/article/info:doi/10.1371/jour...
MTB/RIF (Xpert) enabled simultaneous screening for tuberculosis (TB) and drug susceptibility in all...
<p>The sequence of diagnostic tests in each algorithm and the action taken based on test results is ...
The global burden of tuberculosis (TB), particularly with multidrug resistance (MDR), is escalating ...
In this pilot study, we evaluated the Xpert® MTB/RIF assay in an active case-finding strategy, using...
<p>Abbreviations: CI, confidence interval; MGIT, Mycobacteria Growth Indicator Tube; PPV, positive p...
<p>RIF = Rifampicin</p><p>INH = Isoniazid</p><p>RIF<sup>R</sup> INH<sup>R</sup> = MDR-TB.</p><p>RIF<...
<div><p>Timely diagnosis of drug-resistant tuberculosis (DR-TB) is beneficial for case treatment and...
Item does not contain fulltextOBJECTIVES: Treatment outcome of MDR-TB is critically dependent on the...