<p>A) Paralysis assay on lines transformed with cDNA expressing other <i>C. elegans</i> GluCl subunits. The proportion of worms that were paralysed by immersion in 1 µM ivermectin for 1 hr is shown. B) Thrashing assay of the lines from panel A. The number of thrashes/minute of the worms following a 1 hr exposure to 1 µM ivermectin is indicated. C) Paralysis assay on worms transformed with cDNAs expressing <i>H. contortus</i> GluCl subunits. D) Thrashing assay at three different concentrations of ivermectin, carried out on some of the lines shown in C). For panels A, B & C, * = statistically significant difference from DA1316 (p≤0.05).</p
University of Technology, Sydney. Faculty of Science.Widespread resistance to chemotherapeutic agent...
Resistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a great impact on the contro...
The anti-nematodal drug ivermectin hyperactivates invertebrate-specific glutamate-gated chloride ch...
<p>N = 3. Asterisks indicate a significant difference (p = <0.05) between the transgenic lines and t...
<p>(<b>A</b>) Synchronized L1 and adult wild-type worms were placed on plates containing the specifi...
Anthelmintic resistance is a major problem in livestock farming, especially of small ruminants, but ...
International audienceIvermectin and moxidectin are the most widely administrated anthelmintic macro...
Abstract The indiscriminate administration of synthetic anthelmintics such as ivermectin contribute...
Abstract: To date, the ivermectin resistance in nematode parasites has been reported and many studie...
Our objective was to determine if the resistance mechanism to moxidectin (MOX) is similar of that to...
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infec...
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infec...
The target site for the anthelmintic action of ivermectin is a family of nematode glutamate-gated ch...
While diseases caused by nematodes remains a considerable drawback for the livestock, agriculture an...
International audienceResistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a grea...
University of Technology, Sydney. Faculty of Science.Widespread resistance to chemotherapeutic agent...
Resistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a great impact on the contro...
The anti-nematodal drug ivermectin hyperactivates invertebrate-specific glutamate-gated chloride ch...
<p>N = 3. Asterisks indicate a significant difference (p = <0.05) between the transgenic lines and t...
<p>(<b>A</b>) Synchronized L1 and adult wild-type worms were placed on plates containing the specifi...
Anthelmintic resistance is a major problem in livestock farming, especially of small ruminants, but ...
International audienceIvermectin and moxidectin are the most widely administrated anthelmintic macro...
Abstract The indiscriminate administration of synthetic anthelmintics such as ivermectin contribute...
Abstract: To date, the ivermectin resistance in nematode parasites has been reported and many studie...
Our objective was to determine if the resistance mechanism to moxidectin (MOX) is similar of that to...
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infec...
Background: The nematode Parascaris univalens is one of the most prevalent parasitic pathogens infec...
The target site for the anthelmintic action of ivermectin is a family of nematode glutamate-gated ch...
While diseases caused by nematodes remains a considerable drawback for the livestock, agriculture an...
International audienceResistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a grea...
University of Technology, Sydney. Faculty of Science.Widespread resistance to chemotherapeutic agent...
Resistance to the anthelmintic macrocyclic lactone ivermectin (IVM) has a great impact on the contro...
The anti-nematodal drug ivermectin hyperactivates invertebrate-specific glutamate-gated chloride ch...