Increased weight, blood glucose and insulin, and impaired glucose tolerance in high fat diet (HFD) mice.

<p><b>A</b>, Weight gain in control mice (white, n = 7) and mice fed a HFD (black, n = 5) and <b>B</b>, plasma glucose concentrations in mice on control (white) or high fat diet (black) over time. <b>C</b>, Serum insulin concentrations in mice after 15 weeks of control or high fat diet. <b>D</b>, Glucose tolerance test in control or high fat fed mice presented as area under curve (AUC) of plasma glucose levels×time, 15 weeks after diet start. *<i>p</i><0.05. Data are means ± SEM.