Inducible genetic targeting of Cdc42 inhibited filopodia formation on immobilized fibrinogen.
- Huzoor Akbar (340517)
- Xun Shang (348052)
- Rehana Perveen (340511)
- Mark Berryman (348053)
- Kevin Funk (340512)
- James F. Johnson (348054)
- Narendra N. Tandon (348055)
- Yi Zheng (113896)
Publication date
February 2013
DOIAbstract
<p>Washed platelets from Cdc42<sup>+/+</sup> (A) and Cdc42<sup>−/−</sup> (B) mice were layered over cover slips coated with fibrinogen (3.0 µg/ml) for 20 minutes. The DIC (top panel) and immuno-fluorescence (bottom panel) images show that platelets from Cdc42<sup>−/−</sup> mice failed to form filopodia on immobilized fibrinogen.</p
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