<p>The LRI response was computed at the center of the cell () and expressed as the area under the concentration-time profiles for 10 hours. Integration was performed expressing the concentrations of in nM and times in min. The ligand concentration is given in nM. The values of () are: a) 100; b) 50; c) 30; d) 15.</p
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
The thermodynamic requirements for the cross-linking model of lymphocyte activation are examined tog...
The reversible combination of a ligand with specific sites on the surface of a receptor is one of th...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
<p>Ligand profiles computed as a function of distance at low cell density () for nM. The -values (s...
A panel of human prostate and cancer cells were seeded at optimized conditions and treated for 72-ho...
<p>A. From each dose-response curve, four different derivatives can be calculated to assess TLR-resp...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
In the presence of agonists, many neurotransmitter receptors interact with regulatory components, re...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
The thermodynamic requirements for the cross-linking model of lymphocyte activation are examined tog...
The reversible combination of a ligand with specific sites on the surface of a receptor is one of th...
<p>Concentration-time profiles of LRI computed at high (, curves a) and low (, curves b) cell densit...
<p>Concentration-distance profiles of internalized ligand-receptor complexes computed for (medium c...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
<p>Concentration responses of L, RS, LRS, and LRI to step changes in the ligand input rate. Two inpu...
<p>Top:2D spatial distributions of internalized ligand-receptor complexes and free receptors (LRI an...
<p>Concentration-time profiles of ligand computed at medium cell density () for nM. These profiles ...
<p>Concentration-time profiles of LRS and LRI computed at two values of the endocytic downregulation...
<p>Ligand profiles computed as a function of distance at low cell density () for nM. The -values (s...
A panel of human prostate and cancer cells were seeded at optimized conditions and treated for 72-ho...
<p>A. From each dose-response curve, four different derivatives can be calculated to assess TLR-resp...
<p>Ligand profiles computed as a function of distance at high cell density () and nM for s (A) and...
In the presence of agonists, many neurotransmitter receptors interact with regulatory components, re...
<p>Spatial distribution of ligand computed at , nM, , , for four cell densities: A) high cell densi...
The thermodynamic requirements for the cross-linking model of lymphocyte activation are examined tog...
The reversible combination of a ligand with specific sites on the surface of a receptor is one of th...