Illustrations of the main type of PrPd deposition as revealed by IHC using SAF84 mAb detected in the brain of TgOvPrP4 mice infected with either C506M3 (A, B), Chandler (C, D), 79A (E, F), or 87V (G, H) scrapie strains.

<p>PrPd was detected as amyloid plaques (A, B, D), fine granular linear and intraneuronal deposits (C, F, G, H). In the case of the 79A strain granular PrP^d deposition was seen within the white matter (E).