Wireless recording of single-unit activity from the mouse dorsal striatum during rotarod running.

<p><b>A.</b> Coronal section of a mouse brain showing superimposed electrode placement targeting the dorsal striatum. This experiment used a 2 by 8, 16 channel microwire electrode array. <b>B.</b> Photo of a mouse during a rotarod task. The wireless telemetry system allows the animal to fall and rest between trials without getting wires tangled up in the testing apparatus, yet is small and light enough that it minimally interferes in the task itself. <b>C.</b> Raster plot and peri-event time histogram of a putative medium spiny projection neuron from the dorsal striatum. The start and end of each trial are marked by triangles. Notice the clear difference in firing rates between the trial state and the resting state. The histogram bin size is 4 seconds. <b>D.</b> Action potential waveform of the neuron shown in C.