Inhibitory effect of SiRNA TNFR on TNF-α-induced genes in HMEC endothelial cells.
- Martine Perrot-Applanat (348536)
- Sophie Vacher (233965)
- Aurore Toullec (348538)
- Irma Pelaez (348540)
- Guillaume Velasco (348542)
- Françoise Cormier (271733)
- Hanan El Sheikh Saad (348544)
- Rosette Lidereau (3496)
- Véronique Baud (318941)
- Ivan Bièche (3492)
Publication date
February 2013
DOIAbstract
a<p>Results are expressed as ratio (in percentage) of the mRNA content in siRNA TNFR-transfected cells stimulated with TNF-α (40 ng/ml) for 4 h to the mRNA content in unstimulated cells. After transfection with siTNFR1 or siTNFR2 RNAs, TNFR1 and TNFR2 expression were strongly inhibited (45 % and 77 %, respectively). Results are expressed as the mean of two different independent experiments.</p
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