Glomerular morphometry in control and programmed offspring.

<p>The areas of the Bowman's capsule and of the capillary tuft in the cross section of glomeruli were assessed as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021232#s2" target="_blank">Materials and Methods</a>. For number of rats, number of screened tissue sections and number of glomeruli counted, see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021232#s2" target="_blank">Materials and Methods</a>. Panels A and B show representative photomicrographs (200×) of HE-stained sagital kidney sections of control and programmed rats, respectively. Arrows indicate glomerular structures. Panel C: quantification of the Bowman's capsule area expressed as a percentage of the control group. Results were statistically analyzed and then converted to percentage values (n = 3; *P<0.001). Panel D: quantification of the capillary tuft area expressed as a percentage of the control group (n = 3; *P<0.001). On the <i>abscissae</i> of panels (C) and (D), the capital letters C and P indicate the control and programmed groups, respectively.