<p>A) feet of a <i>Gnas</i> −m/+ male compared to WT (wild type) male at 12 months of age; B) ear of a <i>Gnas</i> −m/+ male at 12 months of age with nodular subcutaneous ossifications; C) X-ray of <i>Gnas</i> −m/+ male at 3 months of age showing occasional subcutaneous ossifications; D) X-ray of 12 month −m/+ obese male with extensive subcutaneous ossifications.</p
Micro-CT scans of naïve joints at 10 weeks (baseline), 16 weeks (6 weeks post in the model) and 29 w...
<p>Histological examination of the skin from the trunk (<a href="http://www.plosone.org/article/info...
<p>(A) Body fat percentage, lean mass and fat mass of wildtype and <i>BubR1</i><sup>+/GTTA</sup> mic...
<p>X-rays of 12 month +/−p and WT mice. A) 12 month +/−p female with no ossifications visualized; B)...
<p>CT scans of 12 month (A–D) and 3 month (E, F) male and female mice with heterozygous targeted dis...
<p>A) Surgically removed area of ossification from a 20 year old male AHO (−p/+) patient with a docu...
<p>(A–B) Body weights of males (A) or females (B) with indicated genotypes. 1: wild type; 2: <i>Osx-...
<p>(A) Skeletal preps of new born mice stained with alizarin red (bone) and alcian blue (cartilage)....
<p>(<b>A</b>) von Kossa staining and toluidine blue staining of the distal femur sections of represe...
Ageing is associated with an increase in visceral obesity in men and women. Although wild-type mice ...
There is significant diversity in growth plate behavior among sites within an individual skeleton an...
<p>A, Micro-computed tomography of the cervical spine of <i>Enpp1<sup>ttw/ttw</sup></i> mice at 12 w...
<p>Upper images in a–f were the μCT views of the whole mandibles, and the lower portions were the cr...
<p>(A) X-ray image of radio-opacities in the skin of a 12-month-old <i>Sml</i> male imaged on a 1×1 ...
INTRODUCTION:Mouse models are used frequently to study effects of bone diseases and genetic determin...
Micro-CT scans of naïve joints at 10 weeks (baseline), 16 weeks (6 weeks post in the model) and 29 w...
<p>Histological examination of the skin from the trunk (<a href="http://www.plosone.org/article/info...
<p>(A) Body fat percentage, lean mass and fat mass of wildtype and <i>BubR1</i><sup>+/GTTA</sup> mic...
<p>X-rays of 12 month +/−p and WT mice. A) 12 month +/−p female with no ossifications visualized; B)...
<p>CT scans of 12 month (A–D) and 3 month (E, F) male and female mice with heterozygous targeted dis...
<p>A) Surgically removed area of ossification from a 20 year old male AHO (−p/+) patient with a docu...
<p>(A–B) Body weights of males (A) or females (B) with indicated genotypes. 1: wild type; 2: <i>Osx-...
<p>(A) Skeletal preps of new born mice stained with alizarin red (bone) and alcian blue (cartilage)....
<p>(<b>A</b>) von Kossa staining and toluidine blue staining of the distal femur sections of represe...
Ageing is associated with an increase in visceral obesity in men and women. Although wild-type mice ...
There is significant diversity in growth plate behavior among sites within an individual skeleton an...
<p>A, Micro-computed tomography of the cervical spine of <i>Enpp1<sup>ttw/ttw</sup></i> mice at 12 w...
<p>Upper images in a–f were the μCT views of the whole mandibles, and the lower portions were the cr...
<p>(A) X-ray image of radio-opacities in the skin of a 12-month-old <i>Sml</i> male imaged on a 1×1 ...
INTRODUCTION:Mouse models are used frequently to study effects of bone diseases and genetic determin...
Micro-CT scans of naïve joints at 10 weeks (baseline), 16 weeks (6 weeks post in the model) and 29 w...
<p>Histological examination of the skin from the trunk (<a href="http://www.plosone.org/article/info...
<p>(A) Body fat percentage, lean mass and fat mass of wildtype and <i>BubR1</i><sup>+/GTTA</sup> mic...