Distribution of antigen-presenting cell subsets in human endometrium.

<p>(a) CD1a+ cells were rare and mainly found within the luminal or glandular epithelium. (b) CD1a+ cells (green) co-expressed (yellow) CD11c+ (red), although not all CD11c+ cells expressed CD1a. (c) The CD1a+ cells (green) also expressed CD4 (red). (d) CD11c+ and (e) CD68+ cells were present in much higher frequencies in both the epithelium and stroma and clusters of both (f) CD11c+ and (g) CD68+ cells were present in the lamina basalis adjacent to glandular epithelium (marked area: 7.1×10⁴ µm² and 8.1×10⁴ µm², respectively). (h) CD123+ cells were solely present in the stroma as scattered cells and in streak formations. (i) Some but not all CD123+ (red) cells co-localized (yellow) with BDCA-2 (green). BDCA-2+ (green) neither co-localized with (j) CD11c+ (red) nor (k) CD68+ (red) cells, although they were occasionally detected in close proximity to each other. Arrowheads indicate example of positive staining. Scale bars: a: 500 µm; b, c, j, k: 25 µm; d–i: 100 µm.