<i>ASF1</i> shows synthetic sick interactions with components of the SWI/SNF complex.

<p>A. <i>asf1Δ snf2Δ</i> double mutants are slower-growing than either single mutant. B. <i>asf1Δ snf2Δ</i> double mutants are slightly temperature-sensitive. Ten-fold serial dilutions of early log phase cells were photographed after 3 days of growth. C. <i>asf1Δ snf5Δ</i> double mutants are slower-growing than either single mutant. Averages of three independent <i>asf1Δ snf5Δ</i> isolates are shown, with error bars (under data point icons).