Effect of heparin upon the ionization constants of prototropic groups from the human neutrophil elastase active site.

Effect of Heparin on Protein Aggregation: Inhibition versus Promotion

Yisheng Xu (1605922)
Daniel Seeman (1869847)
Yunfeng Yan (1559872)
Lianhong Sun (1836931)
Jared Post (2084209)
Paul L. Dubin (1836934)

May 2012

The effect of heparin on both native and denatured protein aggregation was investigated by turbidime...

Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G

Sissi, Claudia
Lucatello, L
Naggi, A
Torri, G
Palumbo, Manlio

January 2006

Semi-synthetic low-molecular-weight heparin samples (LMWHs), having homogeneous degree of polymeriza...

Low-affinity heparin stimulates the inactivation of plasminogen activator inhibitor-1 by thrombin

Patston, P. A.
Schapira, M.

August 1994

The influence of heparin on the reaction between thrombin and plasminogen activator inhibitor-1 (PAI...

Inhibition of human leukocyte elastase activity by heparins: Influence of charge density

Volpi, Nicola

January 1996

Heparins with different structures and physico-chemical properties were evaluated for their capacity...

Effects of heparin and related molecules upon neutrophil aggregation and elastase release in vitro

Brown, R A
Lever, R
Jones, N A
Page, C P

June 2003

1 Neutrophil-derived elastase is an enzyme implicated in the pathogenesis of chronic obstructive pul...

Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.

Gabriel L C Nunes
Alyne Simões
Fábio H Dyszy
Claudio S Shida
Maria A Juliano
Luiz Juliano
Tarsis F Gesteira
Helena B Nader
Gillian Murphy
Alain F Chaffotte
Michel E Goldberg
Ivarne L S Tersariol
Paulo C Almeida

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1) Degradation by the Human Neutrophil Elastase

NUNES, Gabriel L. C.
SIMOES, Alyne
DYSZY, Fabio H.
SHIDA, Claudio S.
JULIANO, Maria A.
JULIANO, Luiz
GESTEIRA, Tarsis F.
NADER, Helena B.
MURPHY, Gillian
CHAFFOTTE, Alain F.
GOLDBERG, Michel E.
TERSARIOL, Ivarne L. S.
ALMEIDA, Paulo C.

January 2011

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1) Degradation by the Human

Neutrophil Elastase
Gabriel L. C. Nunes
Fábio H. Dyszy
Claudio S. Shida
Maria A. Juliano
Tarsis F. Gesteira
Helena B. Nader
Gillian Murphy
Alain F. Chaffotte
Michel E. Goldberg
Ivarne L. S. Tersariol
Paulo C. Almeida

August 2016

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Demonstration of a two-step reaction mechanism for the inhibition of heparin-bound neutrophil elastase by alpha 1-proteinase inhibitor.

Faller, M
Cadene, Martine
Bieth, J

September 1993

International audienceHeparin decreases the rate of inhibition of neutrophil elastase by alpha 1-pro...

Interaction of heparin cofactor II with neutrophil elastase and cathepsin G.

Pratt, C W
Tobin, R B
Church, F C

January 1990

We investigated the interaction of the human plasma proteinase inhibitor heparin cofactor II (HC) wi...

Immunomodulating activity of heparin: evaluation of structure and physico-chemical properties of heparin

VOLPI, Nicola
BOLOGNANI, Lorenzo
Venturelli, T.

January 1992

Immunomodulating activity of heparin: evaluation of structure and physico-chemical properties of hep...

Effects of heparinoids on bovine aortic smooth muscle cells

Asa, Darwin J.

Smooth muscle cells (SMCs) comprise the bulk of the tunica media of all blood vessels. Upon injury t...

Heparin affects the interaction of kininogen on endothelial cells

GOZZO, Andrezza J.
MOTTA, Guacyara
CRUZ-SILVA, Ilana
NUNES, Viviane A.
BARROS, Nilana M. T.
CARMONA, Adriana K.
SAMPAIO, Misako U.
MICHELACCI, Yara M. C.
SHIMAMOTO, Kazuaki
NADER, Helena B.
ARAUJO, Mariana S.

January 2011

In the plasma kallikrein-kinin system, it has been shown that when plasma prekallikrein (PM) and hig...

Maureane Hoffman
Charlotte W. Pratt
Lisa W. Corbin
Frank C. Church

March 2015

The physiological function of the serpin (serine proteinase inhibitor) heparin cofactor II (HCII) is...

Steady-state kinetic parameters for hydrolysis of fluorogenic substrates by human neutrophil elastase in the presence of heparin.

Gabriel L. C. Nunes (349288)
Alyne Simões (349290)
Fábio H. Dyszy (349292)
Claudio S. Shida (349294)
Maria A. Juliano (92351)
Luiz Juliano (56592)
Tarsis F. Gesteira (232845)
Helena B. Nader (232878)
Gillian Murphy (152249)
Alain F. Chaffotte (349297)
Michel E. Goldberg (349299)
Ivarne L. S. Tersariol (232874)
Paulo C. Almeida (349302)

February 2013

a<p>Reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021525#pone.002...

Effect of Heparin on Protein Aggregation: Inhibition versus Promotion

Yisheng Xu (1605922)
Daniel Seeman (1869847)
Yunfeng Yan (1559872)
Lianhong Sun (1836931)
Jared Post (2084209)
Paul L. Dubin (1836934)

May 2012

The effect of heparin on both native and denatured protein aggregation was investigated by turbidime...

Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G

Sissi, Claudia
Lucatello, L
Naggi, A
Torri, G
Palumbo, Manlio

January 2006

Semi-synthetic low-molecular-weight heparin samples (LMWHs), having homogeneous degree of polymeriza...

Low-affinity heparin stimulates the inactivation of plasminogen activator inhibitor-1 by thrombin

Patston, P. A.
Schapira, M.

August 1994

The influence of heparin on the reaction between thrombin and plasminogen activator inhibitor-1 (PAI...

Inhibition of human leukocyte elastase activity by heparins: Influence of charge density

Volpi, Nicola

January 1996

Heparins with different structures and physico-chemical properties were evaluated for their capacity...

Effects of heparin and related molecules upon neutrophil aggregation and elastase release in vitro

Brown, R A
Lever, R
Jones, N A
Page, C P

June 2003

1 Neutrophil-derived elastase is an enzyme implicated in the pathogenesis of chronic obstructive pul...

Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.

Gabriel L C Nunes
Alyne Simões
Fábio H Dyszy
Claudio S Shida
Maria A Juliano
Luiz Juliano
Tarsis F Gesteira
Helena B Nader
Gillian Murphy
Alain F Chaffotte
Michel E Goldberg
Ivarne L S Tersariol
Paulo C Almeida

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1) Degradation by the Human Neutrophil Elastase

NUNES, Gabriel L. C.
SIMOES, Alyne
DYSZY, Fabio H.
SHIDA, Claudio S.
JULIANO, Maria A.
JULIANO, Luiz
GESTEIRA, Tarsis F.
NADER, Helena B.
MURPHY, Gillian
CHAFFOTTE, Alain F.
GOLDBERG, Michel E.
TERSARIOL, Ivarne L. S.
ALMEIDA, Paulo C.

January 2011

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Mechanism of Heparin Acceleration of Tissue Inhibitor of Metalloproteases-1 (TIMP-1) Degradation by the Human

Neutrophil Elastase
Gabriel L. C. Nunes
Fábio H. Dyszy
Claudio S. Shida
Maria A. Juliano
Tarsis F. Gesteira
Helena B. Nader
Gillian Murphy
Alain F. Chaffotte
Michel E. Goldberg
Ivarne L. S. Tersariol
Paulo C. Almeida

August 2016

Heparin has been shown to regulate human neutrophil elastase (HNE) activity. We have assessed the re...

Demonstration of a two-step reaction mechanism for the inhibition of heparin-bound neutrophil elastase by alpha 1-proteinase inhibitor.

Faller, M
Cadene, Martine
Bieth, J

September 1993

International audienceHeparin decreases the rate of inhibition of neutrophil elastase by alpha 1-pro...

Interaction of heparin cofactor II with neutrophil elastase and cathepsin G.

Pratt, C W
Tobin, R B
Church, F C

January 1990

We investigated the interaction of the human plasma proteinase inhibitor heparin cofactor II (HC) wi...

Immunomodulating activity of heparin: evaluation of structure and physico-chemical properties of heparin

VOLPI, Nicola
BOLOGNANI, Lorenzo
Venturelli, T.

January 1992

Immunomodulating activity of heparin: evaluation of structure and physico-chemical properties of hep...

Effects of heparinoids on bovine aortic smooth muscle cells

Asa, Darwin J.

Smooth muscle cells (SMCs) comprise the bulk of the tunica media of all blood vessels. Upon injury t...

Heparin affects the interaction of kininogen on endothelial cells

GOZZO, Andrezza J.
MOTTA, Guacyara
CRUZ-SILVA, Ilana
NUNES, Viviane A.
BARROS, Nilana M. T.
CARMONA, Adriana K.
SAMPAIO, Misako U.
MICHELACCI, Yara M. C.
SHIMAMOTO, Kazuaki
NADER, Helena B.
ARAUJO, Mariana S.

January 2011

In the plasma kallikrein-kinin system, it has been shown that when plasma prekallikrein (PM) and hig...

Maureane Hoffman
Charlotte W. Pratt
Lisa W. Corbin
Frank C. Church

March 2015

The physiological function of the serpin (serine proteinase inhibitor) heparin cofactor II (HCII) is...

Steady-state kinetic parameters for hydrolysis of fluorogenic substrates by human neutrophil elastase in the presence of heparin.

Gabriel L. C. Nunes (349288)
Alyne Simões (349290)
Fábio H. Dyszy (349292)
Claudio S. Shida (349294)
Maria A. Juliano (92351)
Luiz Juliano (56592)
Tarsis F. Gesteira (232845)
Helena B. Nader (232878)
Gillian Murphy (152249)
Alain F. Chaffotte (349297)
Michel E. Goldberg (349299)
Ivarne L. S. Tersariol (232874)
Paulo C. Almeida (349302)

February 2013

a<p>Reference <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0021525#pone.002...

Effect of Heparin on Protein Aggregation: Inhibition versus Promotion

Yisheng Xu (1605922)
Daniel Seeman (1869847)
Yunfeng Yan (1559872)
Lianhong Sun (1836931)
Jared Post (2084209)
Paul L. Dubin (1836934)

May 2012

The effect of heparin on both native and denatured protein aggregation was investigated by turbidime...

Interactions of low-molecular-weight semi-synthetic sulfated heparins with human leukocyte elastase and human Cathepsin G

Sissi, Claudia
Lucatello, L
Naggi, A
Torri, G
Palumbo, Manlio

January 2006

Semi-synthetic low-molecular-weight heparin samples (LMWHs), having homogeneous degree of polymeriza...

Low-affinity heparin stimulates the inactivation of plasminogen activator inhibitor-1 by thrombin

Patston, P. A.
Schapira, M.

August 1994

The influence of heparin on the reaction between thrombin and plasminogen activator inhibitor-1 (PAI...

Effect of heparin upon the ionization constants of prototropic groups from the human neutrophil elastase active site.

Abstract

Extracted data

Effect of heparin upon the ionization constants of prototropic groups from the human neutrophil elastase active site.

Abstract

Extracted data

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