<p>A) Survival of wild type <i>B. pseudomallei</i> K96243 in murine macrophages in RPMI<sup>+</sup> medium containing 250 µg/ml of kanamycin with (▪) or without (□) 5 mM d-alanine. B) Survival of the isogenic alanine racemase deficient mutant strain Δ<i>bpsl2179</i>/Δ<i>bpss0711</i> in murine macrophages in RPMI<sup>+</sup> medium containing 250 µg/ml of kanamycin with (▪) or without (□) 5 mM d-alanine.</p
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
<p>(<b>A</b>) Recapitulation of the B lineage phenotype by successive introduction of mutations in t...
Mutants of a wild-type B. subtilis strain, SB 19, were selected for their inability to metabolize L-...
<p>Murine peritoneal periodate-elicited macrophages were infected in vitro with wild type or alanine...
<p>Immediately after the phagocytosis phase of macrophage killing assays, the macrophages were fixed...
<p>In contrast, the isogenic parental strains of <i>B. pseudomallei</i> and <i>B. mallei</i> grew no...
<p>Overnight cultures of the wild type, Δ<i>bpsl2179/</i>Δ<i>bpss0711</i> mutant, and Δ<i>bpsl2179/<...
Burkholderia pseudomallei and Burkholderia mallei are category B select agents and must be studied u...
<p>(<b>A</b>) BALB/c mice were intranasally infected with <i>B. pseudomallei</i> E8 wild-type, or mu...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
Murine J774A.1 macrophages were infected with either B. pseudomallei wild-type K96243 or its ΔqseBC ...
<p>Survival of BALB/c mice inoculated <i>via</i> the intranasal route with <i>B</i>. <i>pseudomallei...
A Burkholderia pseudomallei mutant which was attenuated in a mouse model of melioidosis was identifi...
<p>Percentage of survival of BALB/c mice challenged intranasally with 2 LD<sub>50</sub> (panel A), 3...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
<p>(<b>A</b>) Recapitulation of the B lineage phenotype by successive introduction of mutations in t...
Mutants of a wild-type B. subtilis strain, SB 19, were selected for their inability to metabolize L-...
<p>Murine peritoneal periodate-elicited macrophages were infected in vitro with wild type or alanine...
<p>Immediately after the phagocytosis phase of macrophage killing assays, the macrophages were fixed...
<p>In contrast, the isogenic parental strains of <i>B. pseudomallei</i> and <i>B. mallei</i> grew no...
<p>Overnight cultures of the wild type, Δ<i>bpsl2179/</i>Δ<i>bpss0711</i> mutant, and Δ<i>bpsl2179/<...
Burkholderia pseudomallei and Burkholderia mallei are category B select agents and must be studied u...
<p>(<b>A</b>) BALB/c mice were intranasally infected with <i>B. pseudomallei</i> E8 wild-type, or mu...
<p>(A) The virulence of the <i>B. pseudomallei</i> K96243 wild-type and <i>bprD</i> mutant strains w...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
Murine J774A.1 macrophages were infected with either B. pseudomallei wild-type K96243 or its ΔqseBC ...
<p>Survival of BALB/c mice inoculated <i>via</i> the intranasal route with <i>B</i>. <i>pseudomallei...
A Burkholderia pseudomallei mutant which was attenuated in a mouse model of melioidosis was identifi...
<p>Percentage of survival of BALB/c mice challenged intranasally with 2 LD<sub>50</sub> (panel A), 3...
<p>(<b>A</b>) Processing of caspases-1, -9, -7 and PARP was detected by immunoblot in cell lysates o...
<p>(<b>A</b>) Recapitulation of the B lineage phenotype by successive introduction of mutations in t...
Mutants of a wild-type B. subtilis strain, SB 19, were selected for their inability to metabolize L-...