Analysis of IL-17 and IL-6 serum concentrations and peripheral CD4+ T cell phenotype.

<p>IL-17 (panel A) and IL-6 (panel B) serum levels were measured in 10 active CAPS patients, 20 active SoJIA patients and 20 healthy controls by ELISA. C–D) <i>Ex-vivo</i> analysis of circulating CCR6⁺ (panel B) and CD161⁺ (panel C) memory T cells (CD4⁺CD45RA⁻) in the same three subgroups. Heterogeneity test among groups was evaluated using the non parametric Kruskal-Wallis test (upper right of each graph). Post-hoc analysis with non-parametric U Mann-Whitney test revealed the difference among the three subgroups.