CAPS patients show an higher absolute number of IL-17 producing cells after <i>in vitro</i> expansion.

<p>A) Dot plot electronically gated on alive CD4⁺ T cells of one representative CINCA patient, one systemic onset juvenile idiopathic arthritis (SoJIA) patient and one healthy control B–C) Absolute number of IL-17 (panel B) and IFN-γ (panel C) producing cells in 7 NLPR3-mutated CAPS and 12 SoJIA active patients and in 9 age-matched healthy controls. Heterogeneity test among groups was evaluated using the non parametric Kruskal-Wallis test (upper right of each graph). Post-hoc analysis with non-parametric U Mann-Whitney test revealed the difference among the three subgroups.