<p>(A) GR downregulation following chronic CORT exposure in neurons. CORT (CORT; 1 µM) was applied to mouse primary cortical neurons at DIV 5. GR protein levels were determined by western blotting analysis at 48 h following CORT treatment. CON means DMSO treatment. Data represent mean±SE (<i>n</i> = 5) expressed as fold change in GR protein levels as compared to CON. *<i>P</i><0.05 (t test). (B) Chronic CORT treatment increases GR protein levels in mouse frontal cortex. GR protein levels in frontal cortex of mice treated with CORT (5 mg/kg) or vehicle control (CON; 0.45% hydroxypropyl-β-cyclodextrin) for 7 weeks were determined by western blot analysis. Data represent mean±SE (<i>n</i> = 5) expressed as fold change in GR protein levels as c...
<p>(<i>A</i>) VEGF protein levels were determined by western blotting analysis in neuronal cell lysa...
Strong evidence shows that oligomeric forms of the amyloid-ß peptide (oAß) cause synapse dysfunction...
The Wobbler mouse spinal cord shows vacuolated motoneurons, glial reaction, inflammation and abnorma...
<p>(<i>A</i>) CORT (CORT; I µM) was applied to mouse primary cortical neurons at DIV 5. Flk1 protein...
<p>(<i>A</i>) Calcium chelator BAPTA-AM blocked CORT (CORT)-induced reduction in Flk1 protein levels...
<p>(<i>A</i>) CORT (CORT; 1 µM) was applied to mouse primary cortical neurons at DIV 5. VEGF protein...
(A) Corticosterone levels in serum from mice euthanized at ZT10, ZT14-fed, and ZT14-unfed. (B) Prepr...
<p>(A, B) Analysis of synapses in brain tissue from wild-type or coronin 1–deficient mice (<i>n</i> ...
<p>The signaling events induced by corticosterone (CORT) are mediated through the Glucocorticoid rec...
<p>Mice were a given ICV injection of GR1 (4 μg) at P10, <b>(a)</b> Real-time PCR showed GR1 reduced...
<p>(A) Western blotting showing CRF protein expression in the hypothalamus 2 hours after the infusio...
<p>(<b>A</b>) Schematic of the behavioral protocol. Rats received either Water or CORT in their drin...
<p>A) GluR1-specific dsRNA reduces GluR1-like but not GluR2-like immunostaining in transduced neuron...
<p>(A) Hippocampal and hypothalamic CORT concentrations of adult mice under normal condition (contro...
48 hours following behavioral testing, DSR-exposed mice of both strains demonstrated significantly r...
<p>(<i>A</i>) VEGF protein levels were determined by western blotting analysis in neuronal cell lysa...
Strong evidence shows that oligomeric forms of the amyloid-ß peptide (oAß) cause synapse dysfunction...
The Wobbler mouse spinal cord shows vacuolated motoneurons, glial reaction, inflammation and abnorma...
<p>(<i>A</i>) CORT (CORT; I µM) was applied to mouse primary cortical neurons at DIV 5. Flk1 protein...
<p>(<i>A</i>) Calcium chelator BAPTA-AM blocked CORT (CORT)-induced reduction in Flk1 protein levels...
<p>(<i>A</i>) CORT (CORT; 1 µM) was applied to mouse primary cortical neurons at DIV 5. VEGF protein...
(A) Corticosterone levels in serum from mice euthanized at ZT10, ZT14-fed, and ZT14-unfed. (B) Prepr...
<p>(A, B) Analysis of synapses in brain tissue from wild-type or coronin 1–deficient mice (<i>n</i> ...
<p>The signaling events induced by corticosterone (CORT) are mediated through the Glucocorticoid rec...
<p>Mice were a given ICV injection of GR1 (4 μg) at P10, <b>(a)</b> Real-time PCR showed GR1 reduced...
<p>(A) Western blotting showing CRF protein expression in the hypothalamus 2 hours after the infusio...
<p>(<b>A</b>) Schematic of the behavioral protocol. Rats received either Water or CORT in their drin...
<p>A) GluR1-specific dsRNA reduces GluR1-like but not GluR2-like immunostaining in transduced neuron...
<p>(A) Hippocampal and hypothalamic CORT concentrations of adult mice under normal condition (contro...
48 hours following behavioral testing, DSR-exposed mice of both strains demonstrated significantly r...
<p>(<i>A</i>) VEGF protein levels were determined by western blotting analysis in neuronal cell lysa...
Strong evidence shows that oligomeric forms of the amyloid-ß peptide (oAß) cause synapse dysfunction...
The Wobbler mouse spinal cord shows vacuolated motoneurons, glial reaction, inflammation and abnorma...