<p>(<b>a</b>) BALB/c mice were immunized <i>id</i> with 1×10<sup>6</sup> pfu MVA85A or 2×10<sup>9</sup> vp Ad85A. Control mice (Naïve) received no immunization. Four weeks later all mice were challenged <i>id</i> with 1×10<sup>5</sup> CFU BCG, contralaterally to the site of vaccination. Ears and LNs were harvested 4 weeks after BCG challenge and processed for CFU quantification. (*<i>P</i><0.05, <i>n</i> = 10 except naïves, <i>n</i> = 5). (<b>b</b>) Corresponding intracellular cytokine staining (ICS) of the local draining LNs. Red bars represent the proportion of IFN-γ-secreting CD4<sup>+</sup> T cells in response to 85A, blue bars represent the same for CD8<sup>+</sup> T cells (M, <i>n</i> = 4; Naïve, <i>n</i> = 3; Ad, <i>n</i> = 4. *<i>P<...
<p><b>A.</b> C57BL/6 mice were subcutaneously vaccinated as previously described (unprimed; white, e...
<p><b>(A)</b> Scheme of immunotherapy experiments. BALB/c mice were infected with a low dose aerosol...
<p><b>a.</b> C57BL/6 mice were immunized once with BCG with or without simultaneous administration o...
<p>Timeline is shown in (<b>a</b>). BALB/c mice were immunized <i>id</i> with 1×10<sup>4</sup> CFU B...
<p>Balb/c mice received BCG±CT <i>i.n.</i> followed by 1×10<sup>6</sup> CFU MVA85A 10 weeks later. L...
<p><b>A</b>. Naïve C57BL/6 mice (black) or mice subcutaneously primed with 10<sup>7</sup> empty-vect...
<p>(A–B) BALB/c mice were vaccinated with 1×10<sup>6</sup> CFU of BCG Copenhagen by intranasal (i.n....
<p><b>A.</b> Naïve C57BL/6 mice (dotted black) or mice subcutaneously primed with empty-vector BCG p...
<p>Mice were primed i.d. with BCG and boosted i.d. at 11 and 17 weeks after the prime with successiv...
<p>Mice were primed with BCG[pWB206] or BCG[pHS207] (intraperitoneal vaccination; doses of 10<sup>7<...
<p><b>A</b> & <b>B</b>) Balb/c mice were immunized i.m. at weeks 0 and 2 with 50 µg of pSG2-Ag85A or...
<p>The infection procedure is described in the Materials and Methods. Six weeks after challenge, ani...
<p>Groups of mice were vaccinated with BCG-Gag, BCG-Control, BCGpan-Gag or BCGpan-Control (10<sup>7<...
<p>(A–C) BCG-vaccinated or age-matched naïve mice were infected with <i>Mtb</i> Erdman, and 6 weeks ...
<p>Groups of mice were primed with BCG-Gag (10<sup>7</sup> cfu) and BCG-Control (10<sup>7</sup> cfu)...
<p><b>A.</b> C57BL/6 mice were subcutaneously vaccinated as previously described (unprimed; white, e...
<p><b>(A)</b> Scheme of immunotherapy experiments. BALB/c mice were infected with a low dose aerosol...
<p><b>a.</b> C57BL/6 mice were immunized once with BCG with or without simultaneous administration o...
<p>Timeline is shown in (<b>a</b>). BALB/c mice were immunized <i>id</i> with 1×10<sup>4</sup> CFU B...
<p>Balb/c mice received BCG±CT <i>i.n.</i> followed by 1×10<sup>6</sup> CFU MVA85A 10 weeks later. L...
<p><b>A</b>. Naïve C57BL/6 mice (black) or mice subcutaneously primed with 10<sup>7</sup> empty-vect...
<p>(A–B) BALB/c mice were vaccinated with 1×10<sup>6</sup> CFU of BCG Copenhagen by intranasal (i.n....
<p><b>A.</b> Naïve C57BL/6 mice (dotted black) or mice subcutaneously primed with empty-vector BCG p...
<p>Mice were primed i.d. with BCG and boosted i.d. at 11 and 17 weeks after the prime with successiv...
<p>Mice were primed with BCG[pWB206] or BCG[pHS207] (intraperitoneal vaccination; doses of 10<sup>7<...
<p><b>A</b> & <b>B</b>) Balb/c mice were immunized i.m. at weeks 0 and 2 with 50 µg of pSG2-Ag85A or...
<p>The infection procedure is described in the Materials and Methods. Six weeks after challenge, ani...
<p>Groups of mice were vaccinated with BCG-Gag, BCG-Control, BCGpan-Gag or BCGpan-Control (10<sup>7<...
<p>(A–C) BCG-vaccinated or age-matched naïve mice were infected with <i>Mtb</i> Erdman, and 6 weeks ...
<p>Groups of mice were primed with BCG-Gag (10<sup>7</sup> cfu) and BCG-Control (10<sup>7</sup> cfu)...
<p><b>A.</b> C57BL/6 mice were subcutaneously vaccinated as previously described (unprimed; white, e...
<p><b>(A)</b> Scheme of immunotherapy experiments. BALB/c mice were infected with a low dose aerosol...
<p><b>a.</b> C57BL/6 mice were immunized once with BCG with or without simultaneous administration o...