Action potential properties in wt and dystrophic adult cardiomyocytes.

<p>Typical AP of a wt cardiomyocyte (top left) elicited by a 4-ms current injection at 125% threshold. On the top right, the upstrokes of typical APs recorded from wt and dystrophic cardiomyocytes are overlayed on an expanded time scale. In the lower panel, maximum upstroke velocity (max. dV/dt), and the maximum depolarisation value reached by the AP (abs. amplitude) are plotted against the membrane potential. * and ** indicate significant differences (ANOVA; p<0.05 and <0.01; n-values: 5–8) between the three tested groups, respectively. Tukey's Post Hoc test revealed no significant differences between mdx-utr and mdx.