RAGE KO mice get less inflammation than wild type mice after <i>E. coli</i> pneumonia.

<p><i>E. coli</i> challenged RAGE KO mice had significantly less total cells/mL in BALF compared to wild type mice (A). The lower amount of cells was mainly due to less neutrophils (B, C). Protein in BALF (D) and myeloperoxidase activity of whole lung (E) were also significantly less in RAGE KO than in wild type mice after <i>E. coli</i> challenge. * indicate significant increase/decrease compared to vehicle control for each strain. ** indicate significant difference between wild type and RAGE KO mice. Data are mean ±SEM, analyzed by 2-way ANOVA with a Bonferroni post hoc test (<i>n of 6–8 per group</i>).