Increased mobilization of <i>Grp94</i> KO HSCs.

<p>A) Representative flow cytometric analysis of splenocytes from WT (n = 9) and cKO (n = 9) mice using Lin, c-Kit and Sca-1 (left) and quantitation (right). In these studies, splenocytes were extracted from WT and cKO mice 5 days after 7 injections of pI.pC (to examine HSC mobilization before the spleen was enlarged). B) Representative flow cytometric analysis of blood MNCs from WT (n = 11) and cKO (n = 10) mice using Lin, c-Kit and Sca-1 (left) and quantitation (right). All data are presented as mean ± s.e., ***p<0.001.