TcVac1-induced antibody response in dogs.

<p>Dogs were vaccinated with TcVac1 or injected with vector only, and sera were collected two weeks after each immunization dose. An ELISA was performed to monitor the sera levels (1∶50 dilution) of parasite-specific IgM (<b>A</b>), IgG (<b>B</b>), IgG1 (<b>C</b>) and IgG2 (<b>D</b>). The vaccine-induced antigen-specific (TcG1, TcG2 and TcG4) antibody response in sera collected 14 days after last dose of vaccine was determined using recombinant antigens. Data are presented as mean ± SD (*<i>p</i><0.05, vaccinated versus non-vaccinated, n = 6 per experiment).