Variation of RNFL measurements.

<p><b>a, b</b>: variation of RNFL measurements between baseline and follow-up examination in relation to the total relapses (without ON) before study entry. <b>c, d</b>: variation of RNFL measurements between baseline and follow-up examination in relation to the relapses (without ON) during the observation period. <b>a</b>, left eye; <b>b</b>, right eye; <b>c</b>, left eye; <b>d</b>, right eye; <b>white squares</b>, RRMS without ON; <b>black squares</b>, RRMS with ON; <b>white triangles</b>, SPMS without ON; <b>black triangles</b>, SPMS with ON.