Evaluation of locomotor recovery over 8 weeks after SCI.

<p>BBB rating scale ranges from a minimum of 0 (no observable hindlimbs movements) to a maximum of 21 (presence of consistent plantar stepping, coordination and trunk stability). At 7.5 weeks after injury, in the treatment group (4G-BMHP1) we observed a better improvement of hindlimbs motor recovery compared to both control groups (saline and SCI control). This statistically relevant difference among scores implies that all groups had frequent or consistent plantar stepping but in the treatment group occurred also an occasional forelimbs-hindlimbs coordination. Values represent means ± SEM. Significance symbols: * p<0.05, 4G-BMHP1 vs SCI control; ° p<0.05, 4G-BMHP1 vs saline.