<p>(<b>A</b>) Nucleotide sequences of the putative NFAT binding sites in the human TRAIL promotor. The 1371 bp TRAIL promoter contains five putative NFAT binding sites (N1, N2, N3, N4, and N5). The numbers on the left are the nucleotide positions relative to the transcriptional start site. (<b>B</b>) HT29 cells were treated with or without PMA/Io for 60 min and nuclear protein extracted; EMSA was performed with <sup>32</sup>P-labeled probes spanning each of the five NFAT binding sites (N1, N2, N3, N4, and N5) in the human TRAIL promoter. (<b>C</b>) Specific binding of various NFAT isoforms with probe N4 or N5 was determined by addition of antibodies to either NFATc1, NFATc2, NFATc3, or NFATc4. Specific binding of NFAT was also confirmed by ...
Nuclear factor of activated T-cells (NFAT) proteins are transcription factors evolutionary related t...
Nuclear factor of activated T cells (NFAT) is a family of transcription factors, named NFATc1-4, tha...
<p>(A) HEK293 cells were transfected with 0.1 µg COX-2 luciferase reporter (COX-2 -luc), 30 ng pRL-T...
<p>(<b>A</b>) Double-stranded oligonucleotides corresponding to all of the potential transcriptional...
<p>HT29 cells were transfected with either the control plasmid (pDF30) or Flag-tagged NFATc1. At 48 ...
<p>HT29 cells were transiently transfected with control siRNA or siRNA targeting NFATc1. Nuclear pro...
<p>(<b>A</b>) HT29 cells were treated with PMA/Io for 60 min and NFAT DNA binding activity was asses...
TNF-related apoptosis-inducing ligand (TRAIL; Apo2) has been shown to promote intestinal cell differ...
<div><p>(A) Disruption of NFAT5 binding does not impair NF-κβ (p50/p65) binding. An EMSA is shown us...
<p>The binding of NFATs to the promoter region was analyzed by chromatin immunoprecipitation-qPCR as...
<p>PC12 cells were transfected with plasmids encoding firefly luciferase under NFAT-dependent promot...
<p>A- NFATC1 extracts from HEK 293 cells transfected with Wt NFATC1 and Mutants (P66L – I701L – P66L...
AbstractThe nuclear factor of the activated T cell (NFAT) family of transcription factors regulates ...
<div><p>(A) NF-κβ, NFATp, and NFAT5 bind to distinct and overlapping sequences in the HIV-1 LTR enha...
<p>A- Wt NFATC1 or NFATC1 Mutants (P66L, I701L, P66L/I701L) were cotransfected with the human CCND1 ...
Nuclear factor of activated T-cells (NFAT) proteins are transcription factors evolutionary related t...
Nuclear factor of activated T cells (NFAT) is a family of transcription factors, named NFATc1-4, tha...
<p>(A) HEK293 cells were transfected with 0.1 µg COX-2 luciferase reporter (COX-2 -luc), 30 ng pRL-T...
<p>(<b>A</b>) Double-stranded oligonucleotides corresponding to all of the potential transcriptional...
<p>HT29 cells were transfected with either the control plasmid (pDF30) or Flag-tagged NFATc1. At 48 ...
<p>HT29 cells were transiently transfected with control siRNA or siRNA targeting NFATc1. Nuclear pro...
<p>(<b>A</b>) HT29 cells were treated with PMA/Io for 60 min and NFAT DNA binding activity was asses...
TNF-related apoptosis-inducing ligand (TRAIL; Apo2) has been shown to promote intestinal cell differ...
<div><p>(A) Disruption of NFAT5 binding does not impair NF-κβ (p50/p65) binding. An EMSA is shown us...
<p>The binding of NFATs to the promoter region was analyzed by chromatin immunoprecipitation-qPCR as...
<p>PC12 cells were transfected with plasmids encoding firefly luciferase under NFAT-dependent promot...
<p>A- NFATC1 extracts from HEK 293 cells transfected with Wt NFATC1 and Mutants (P66L – I701L – P66L...
AbstractThe nuclear factor of the activated T cell (NFAT) family of transcription factors regulates ...
<div><p>(A) NF-κβ, NFATp, and NFAT5 bind to distinct and overlapping sequences in the HIV-1 LTR enha...
<p>A- Wt NFATC1 or NFATC1 Mutants (P66L, I701L, P66L/I701L) were cotransfected with the human CCND1 ...
Nuclear factor of activated T-cells (NFAT) proteins are transcription factors evolutionary related t...
Nuclear factor of activated T cells (NFAT) is a family of transcription factors, named NFATc1-4, tha...
<p>(A) HEK293 cells were transfected with 0.1 µg COX-2 luciferase reporter (COX-2 -luc), 30 ng pRL-T...