Comparison of the image derived values of MDI and VSI to CD31 positive endothelial cell staining.

<p>(A) a vehicle treated (upper row) tumor presenting a high microvessel density index (MDI (1/mm²)) in MRI and a low vessel index (VSI (µm)). The PTK787-treated tumor (lower row) presents low MDI values with high VSI values. (B) correlation between CD31 positive vessels per area unit and the imaged derived MDI values (n = 10).