Design of ZFRs, Z-sites and test substrates.

<p>(<b>A</b>) Cartoon showing a Tn<i>3</i> resolvase dimer bound to <i>res</i> site I. The red ovals represent the N-terminal (catalytic) and C-terminal (DNA-binding) domains. The motifs recognized by the C-terminal domains are yellow, and the central 12 bp segment (pink) is contacted by the catalytic domains.(<b>B</b>) Cartoon showing a ZFR dimer bound to a Z-site. The zinc finger domains are blue, the motifs they recognize are pale blue, and the ZFR linker peptide is green. Other features are as in <b>A</b>.