<p>The synaptic blocker cocktail consisted of a mixture of excitatory and inhibitory neurotransmitter blockers including L-(+)-2-Amino-4-phosphonobutyric acid (AP-4, 100 µM), 6,7-Dinitroquinoxaline-2,3-dione (DNQX, 20 µM), DL-2-amino-5-phosphonovaleric acid (AP5, 50 µM), Picrotoxin (50 µM ) Strychnine (0.3 µM), and hexamethonimm bromide (200 µM) was added to the oxygenated Ames' medium. (<b>A</b>) visual responses of an ON center (upper) and (<b>C</b>) an OFF center (lower) DRN-projecting RGCs before synaptic transmission blockade. (<b>B</b>) and (<b>D</b>) response patterns of the cells after synaptic transmission blockade. The retinal irradiance of the stimuli was 6.4×10<sup>13</sup> photons/cm<sup>2</sup>/sec, λ = 475 nm, and stimulation...
<p><b>A</b>. Visual responses to an optimally oriented moving light bar of a 4RSN recorded under 1 m...
<div><p>(A) Schematic demonstrating natural activity resulting from retinal waves in the retina (top...
International audience• Stimulation of a dissected retina with a sequence of periodic dark flashes. ...
<p>(A) Light responses evoked by 2s flash of light at indicated intensities (Log10 Rh*/rod/s) before...
<p>Representative averaged traces from a variety of INL cell types in the <i>rd/rd</i> retina, black...
<p>A: Trial bin count examples of two cells responding to a 71% contrast step (blue bar at 0 to 20 s...
<p>Representative averaged traces from a variety of INL cell types in the wild-type retina, black tr...
<p>The cocktail of blockers contained (in μM): 50 L-AP4, 10 bicuculline, 10 strychnine, 50 D-AP5, an...
<p>Number of excitatory (A) and suppressive (B) components before and after application of synaptic ...
<p>Responses of 3 units (mean and standard deviation of 10 measurements) to flashed and moving ON (A...
<p>(<b>A</b>) (Left) MIP of an ON-S A-type RGC labeled by biolistic transfection of tdTomato and PSD...
<p>A) A raster plot of spike times for a sample cell prior to application of CdCl<sub>2</sub>. B) Th...
<p>(A) A cocktail of neurotransmitter antagonists effectively eliminate the light-evoked responses o...
International audience• Stimulation a dissected retina with a sequence of periodic dark flashes • Ex...
The visual system transmits information about fast and slow changes in light intensity through separ...
<p><b>A</b>. Visual responses to an optimally oriented moving light bar of a 4RSN recorded under 1 m...
<div><p>(A) Schematic demonstrating natural activity resulting from retinal waves in the retina (top...
International audience• Stimulation of a dissected retina with a sequence of periodic dark flashes. ...
<p>(A) Light responses evoked by 2s flash of light at indicated intensities (Log10 Rh*/rod/s) before...
<p>Representative averaged traces from a variety of INL cell types in the <i>rd/rd</i> retina, black...
<p>A: Trial bin count examples of two cells responding to a 71% contrast step (blue bar at 0 to 20 s...
<p>Representative averaged traces from a variety of INL cell types in the wild-type retina, black tr...
<p>The cocktail of blockers contained (in μM): 50 L-AP4, 10 bicuculline, 10 strychnine, 50 D-AP5, an...
<p>Number of excitatory (A) and suppressive (B) components before and after application of synaptic ...
<p>Responses of 3 units (mean and standard deviation of 10 measurements) to flashed and moving ON (A...
<p>(<b>A</b>) (Left) MIP of an ON-S A-type RGC labeled by biolistic transfection of tdTomato and PSD...
<p>A) A raster plot of spike times for a sample cell prior to application of CdCl<sub>2</sub>. B) Th...
<p>(A) A cocktail of neurotransmitter antagonists effectively eliminate the light-evoked responses o...
International audience• Stimulation a dissected retina with a sequence of periodic dark flashes • Ex...
The visual system transmits information about fast and slow changes in light intensity through separ...
<p><b>A</b>. Visual responses to an optimally oriented moving light bar of a 4RSN recorded under 1 m...
<div><p>(A) Schematic demonstrating natural activity resulting from retinal waves in the retina (top...
International audience• Stimulation of a dissected retina with a sequence of periodic dark flashes. ...