Soluble Aβ triggers caspase-3 expression in Tg2576 cortical neurons.
- Shannon Ray (243989)
- Claire Howells (243967)
- Emma D. Eaton (243969)
- Chris W. Butler (332418)
- Lana Shabala (243971)
- Paul A. Adlard (31148)
- Adrian K. West (243994)
- William R. Bennett (243986)
- Gilles J. Guillemin (133306)
- Roger S. Chung (243965)
Publication date
February 2013
DOIAbstract
<p>Tg2576 neurons cultured for 14 days <i>in vitro</i> (DIV) showed no signs of caspase-3 activation (A). However, when 7 DIV Tg2576 neurons were treated with 1 µM Aβ<sub>1-40</sub> daily for 6 days, a substantial number of neurons were found to express caspase-3 (B).</p
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