<p>Treatment with 1 µM Aβ<sub>1-40</sub> triggered rapid efflux of K<sup>+</sup> from Tg2576 neurons (A), which continued over the 120 minutes of recording. Aβ<sub>1-40</sub> treatment caused a rapid influx of H<sup>+</sup> in Tg2576 neurons (B), which did not stabilise over the 120 minute recording period.</p
<p>(<b>a</b>) Induction of CA1- LTP after HFS in control hippocampal slices (Two-way ANOVA p = 0.000...
<p>Mature cortical neurons were treated with supernatants containing α<b><sub>V</sub></b>β<b><sub>3<...
Summary: A mixed mesencephalic cell culture damaged by glutamate was used as a model to study the ef...
<p>Tg2576 neurons cultured for 14 days <i>in vitro</i> (DIV) showed no signs of caspase-3 activation...
<p>Wildtype and Tg2576 cortical neurons were treated with 10 µM of monomeric Aβ<sub>1-40</sub>, and ...
<p>(A) The effect of 100 nM JZTX-III on current recordings from HEK-293 cells transfected with the K...
<p>Rat primary cortical cells were cultured for three weeks and subsequently exposed to either 100 μ...
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterised by th...
<p>Tau immunolabelling of the axonal cytoskeleton demonstrated that axonal morphology was similar be...
BACKGROUND: One of the key pathological features of AD is the formation of insoluble amyloid plaques...
<p>(A) Ca<sup>2+</sup> influx in neurons measured by Fluo-4 fluorescence. Fluo-4-loaded neurons were...
Net K fluxes in in vitro suspensions of sliced rat brain cortex were studied by means of a K-sensiti...
Background: One of the key pathological features of AD is the formation of insoluble amyloid plaques...
<p>Panel A: Aβ oligomers triggers the release of m-HKI from mitochondria. Western immunoblot analysi...
<p>Brains from mice aged 12 months were homogenized and separated into soluble (c, d) and insoluble ...
<p>(<b>a</b>) Induction of CA1- LTP after HFS in control hippocampal slices (Two-way ANOVA p = 0.000...
<p>Mature cortical neurons were treated with supernatants containing α<b><sub>V</sub></b>β<b><sub>3<...
Summary: A mixed mesencephalic cell culture damaged by glutamate was used as a model to study the ef...
<p>Tg2576 neurons cultured for 14 days <i>in vitro</i> (DIV) showed no signs of caspase-3 activation...
<p>Wildtype and Tg2576 cortical neurons were treated with 10 µM of monomeric Aβ<sub>1-40</sub>, and ...
<p>(A) The effect of 100 nM JZTX-III on current recordings from HEK-293 cells transfected with the K...
<p>Rat primary cortical cells were cultured for three weeks and subsequently exposed to either 100 μ...
Background: Alzheimer's disease (AD) is a progressive neurodegenerative disease, characterised by th...
<p>Tau immunolabelling of the axonal cytoskeleton demonstrated that axonal morphology was similar be...
BACKGROUND: One of the key pathological features of AD is the formation of insoluble amyloid plaques...
<p>(A) Ca<sup>2+</sup> influx in neurons measured by Fluo-4 fluorescence. Fluo-4-loaded neurons were...
Net K fluxes in in vitro suspensions of sliced rat brain cortex were studied by means of a K-sensiti...
Background: One of the key pathological features of AD is the formation of insoluble amyloid plaques...
<p>Panel A: Aβ oligomers triggers the release of m-HKI from mitochondria. Western immunoblot analysi...
<p>Brains from mice aged 12 months were homogenized and separated into soluble (c, d) and insoluble ...
<p>(<b>a</b>) Induction of CA1- LTP after HFS in control hippocampal slices (Two-way ANOVA p = 0.000...
<p>Mature cortical neurons were treated with supernatants containing α<b><sub>V</sub></b>β<b><sub>3<...
Summary: A mixed mesencephalic cell culture damaged by glutamate was used as a model to study the ef...