The simulated sensitivity of distinct agonists to loss of receptors (in percentage).
- Vasiliy Goral (352639)
- Yan Jin (143500)
- Haiyan Sun (201818)
- Ann M. Ferrie (352641)
- Qi Wu (263110)
- Ye Fang (60292)
Publication date
February 2013
DOIAbstract
<p>(a) The effect of an EC<sub>100</sub> of each agonist (calculated where the total receptor is unchanged; <i>R<sub>T</sub></i> = 100) at different receptor numbers. Data were normalized to percentage of the response at the EC<sub>100</sub> where <i>R<sub>T</sub></i> = 100. (d) The function of <i>E<sub>max</sub></i> achievable by the agonists as receptor loss.</p
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