Host gene expression on day 1 after SARS-CoV infection.
- Barry Rockx (151946)
- Friederike Feldmann (151957)
- Douglas Brining (151975)
- Don Gardner (92779)
- Rachel LaCasse (191745)
- Lisa Kercher (151969)
- Dan Long (151972)
- Rebecca Rosenke (191750)
- Kimmo Virtaneva (352991)
- Daniel E. Sturdevant (224381)
- Stephen F. Porcella (42449)
- John Mattoon (352993)
- Michael Parnell (352994)
- Ralph S. Baric (163960)
- Heinz Feldmann (18301)
Publication date
February 2013
DOIAbstract
<p>(A) The number of differentially expressed genes are the result of a comparison of gene expression in the lungs of SARS-CoV infected cynomolgus macaques versus gene expression in the lungs of mock-infected animals, and genes were included if they met the criteria of an absolute change of ≥2-fold (P≤0.05. (B) The Venn diagram shows the overlap of unique and common genes with ≥2-fold (P≤0.01) between Urbani, GZ02 and HC/SZ/61/03. Functional annotations (C) and canonical pathways (D) were determined in order to better understand the biological functions associated with SARS-CoV infection in cynomolgus macaques.</p
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