<p>Anesthetized mice received intranasal administration of CTG (6 µl) or vehicle (PBS). Mice remained anesthetized for an additional 20 minutes in a supine position. Five hours later, mice were euthanized and perfused with 4% PFA, and the brains sectioned into 12 µm slices. Nuclei were counterstained with DAPI (Blue). CTG cells are labeled green. No signal was detected in the vehicle treated mice (data not shown).</p
(A) Western blot probing for cleaved caspase-3 in brain lysates from control P7 mice (unexposed) and...
<p>(<b>A</b>) Olfactory epithelium after intranasal application of 5 µl blue dye. EOGs were measured...
<p><b>A.</b> Confocal fluorescent image of anti-CCK<sub>B</sub> receptor antibody binding to a horiz...
<p>Anesthetized mice received intranasal administration of CTG (6 µl) or vehicle (PBS) into both nar...
<p>Mice were anesthetized and the RMS dissected through a small burr-hole over the olfactory bulb. <...
Nasal drug delivery in rodents is a challenging procedure, especially for brain targeting, as the po...
<p>Female BALB/c mice were administered 10 μl or 50 μl of contrast medium by eyedrop or IN, respecti...
<p>Light microscopic analysis after anti-tyrosine hydroxylase (TH) staining of the olfactory bulb (O...
<p>CLN3<sup>Δex7/8</sup> and wild type (WT) mice were treated with INI-0602 (10 mg/kg) or PBS from p...
Bone marrow-derived mesenchymal stromal cells (MSCs) hold promise for autologous treatment of neurop...
<p>Mice were i.v. injected with GFP-Etx-I51C/A114C (A–B) or GFP-Etx-V56C/A118C (C–D) in combination ...
Fluorescent images of nasal concha from mice administered (a) no FITC-GC or (b-f) 0.75% FITC-GC i.n....
<p>BALB/c mice (11–13 per group) were sensitized by intranasal administration of 100 µg of ovalbumin...
<p>3xTg-AD mice (13 month-old) were intranasally administrated with S14G-HN (B) or vehicle (A), and ...
<p>OE and OBs were obtained at 0 (untreated), 24, or 72 h after nasal administration of 30 μg CT. (<...
(A) Western blot probing for cleaved caspase-3 in brain lysates from control P7 mice (unexposed) and...
<p>(<b>A</b>) Olfactory epithelium after intranasal application of 5 µl blue dye. EOGs were measured...
<p><b>A.</b> Confocal fluorescent image of anti-CCK<sub>B</sub> receptor antibody binding to a horiz...
<p>Anesthetized mice received intranasal administration of CTG (6 µl) or vehicle (PBS) into both nar...
<p>Mice were anesthetized and the RMS dissected through a small burr-hole over the olfactory bulb. <...
Nasal drug delivery in rodents is a challenging procedure, especially for brain targeting, as the po...
<p>Female BALB/c mice were administered 10 μl or 50 μl of contrast medium by eyedrop or IN, respecti...
<p>Light microscopic analysis after anti-tyrosine hydroxylase (TH) staining of the olfactory bulb (O...
<p>CLN3<sup>Δex7/8</sup> and wild type (WT) mice were treated with INI-0602 (10 mg/kg) or PBS from p...
Bone marrow-derived mesenchymal stromal cells (MSCs) hold promise for autologous treatment of neurop...
<p>Mice were i.v. injected with GFP-Etx-I51C/A114C (A–B) or GFP-Etx-V56C/A118C (C–D) in combination ...
Fluorescent images of nasal concha from mice administered (a) no FITC-GC or (b-f) 0.75% FITC-GC i.n....
<p>BALB/c mice (11–13 per group) were sensitized by intranasal administration of 100 µg of ovalbumin...
<p>3xTg-AD mice (13 month-old) were intranasally administrated with S14G-HN (B) or vehicle (A), and ...
<p>OE and OBs were obtained at 0 (untreated), 24, or 72 h after nasal administration of 30 μg CT. (<...
(A) Western blot probing for cleaved caspase-3 in brain lysates from control P7 mice (unexposed) and...
<p>(<b>A</b>) Olfactory epithelium after intranasal application of 5 µl blue dye. EOGs were measured...
<p><b>A.</b> Confocal fluorescent image of anti-CCK<sub>B</sub> receptor antibody binding to a horiz...