<p>*For SP, the remainder is divided 50:50 between single/double and triple <i>dhfr</i> mutations.</p
<p>(A) Residue root mean square fluctuations (RMSF) are provided for the six molecular dynamics traj...
<p>We test our simulation procedure against the analytic results of the set model of <a href="http:/...
<p>Description is the same as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Error number and error rate describe the number and fraction of mutations not predicted in the co...
<p>As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076195#pone-0076195-...
<p><b>NOTE.</b> CI, confidence interval; OR, odds ratio; SP, sulfadoxine-pyrimethamine; CTX, cotrimo...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>(A) The MD simulations of 1-17-2 Fab and the 30 mutants. The curves indicate the RMSD value chang...
<p>This matrix displays the results of systematic perturbations. Loss- and gain-of-function mutation...
<p>Dashes denote cases where the known mutation was not enriched in the predicted sequences using no...
<p>The left part of the distribution remains unchanged, while the right tail gets closer to a unifor...
The mutation proportions used to generate the model that determined the number of stop codons produc...
<p>Description is the same as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>(a) SFS generated under fluctuating conditions. The proportion of mutations with positive and neg...
<p>The fixation number of mutations in simulation as a function of the dominance coefficient <i>h</i...
<p>(A) Residue root mean square fluctuations (RMSF) are provided for the six molecular dynamics traj...
<p>We test our simulation procedure against the analytic results of the set model of <a href="http:/...
<p>Description is the same as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>Error number and error rate describe the number and fraction of mutations not predicted in the co...
<p>As in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0076195#pone-0076195-...
<p><b>NOTE.</b> CI, confidence interval; OR, odds ratio; SP, sulfadoxine-pyrimethamine; CTX, cotrimo...
<p>The true positive rate (TPR, row 1), false discovery rate (FDR, row 2) and false positive rate (F...
<p>(A) The MD simulations of 1-17-2 Fab and the 30 mutants. The curves indicate the RMSD value chang...
<p>This matrix displays the results of systematic perturbations. Loss- and gain-of-function mutation...
<p>Dashes denote cases where the known mutation was not enriched in the predicted sequences using no...
<p>The left part of the distribution remains unchanged, while the right tail gets closer to a unifor...
The mutation proportions used to generate the model that determined the number of stop codons produc...
<p>Description is the same as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...
<p>(a) SFS generated under fluctuating conditions. The proportion of mutations with positive and neg...
<p>The fixation number of mutations in simulation as a function of the dominance coefficient <i>h</i...
<p>(A) Residue root mean square fluctuations (RMSF) are provided for the six molecular dynamics traj...
<p>We test our simulation procedure against the analytic results of the set model of <a href="http:/...
<p>Description is the same as for <a href="http://www.plosone.org/article/info:doi/10.1371/journal.p...