SFA inhibits cytokine-cytokine receptor interactions.

<p>Human moDCs were treated with 1 µM SFA or vehicle for 1 hour and total RNA was prepared after 12 h stimulation with 1 µg/mL LPS. The cDNA were labelled with Cy3- and Cy5-fluorescent dyes for microarray hybridization. Chart summarizes the results of the pathway impact analysis. Numbers indicate the impact factor. The impact factor is calculated based on the normalized fold of gene expression change, the number and amount of perturbation of genes downstream from it and the proportion of differentially regulated genes in the respective pathway <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0018406#pone.0018406-Khatri1" target="_blank">[25]</a>.