<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar amount of brain tissue equivalent (20 µg) was loaded for adequate comparison. vCJD isolate was loaded for comparison. Molecular weights (in kDa) are shown at the left side of the blot. Similar PrP<sup>res</sup> banding patterns were observed in the vCJD- and the cattle, sheep and goat BSE-challenged tg650 mice.</p
<p>Electrophoretic profiles and antibody labelling of PrP<sup>res</sup> as detected by mAbs Sha31 (A...
<p>All mice were inoculated with the same vCJD prion isolate. Immunoblots were analysed by enhanced ...
<p>Labelling for PrP<sup>d</sup> in the brain (indicated by brown staining) from several ruminant sp...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar quantities of PrP<sup>re...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 and 12B2 mAbs. Similar quantities of ...
<div><p>(A) Primary or secondary (lane 6) transmission to tgBov mice. BSE-type inocula include cattl...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>Histoblots of 4 representative anteroposterior mouse brain sections are shown. Comparison has bee...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 mAb. Direct sample and 1/5 dilutions ...
<p>Electrophoretic profiles and antibody labelling of PrP<sup>res</sup> as detected by mAbs Sha31 (A...
<p>PMCA reactions were seeded with BSE brain material (10<sup>−2</sup> dilution) from different spec...
<p>Homogenates were subjected to proteinase K digestion followed by immunoblotting using Sha31 monoc...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>Each lane represents PK-digested PrP<sup>Sc</sup> probed with an anti-PrP monoclonal antibody. Mo...
<p>PrP<sup>res</sup> was detected by western blot using the mAbs Sha31 (A) and 12B2 (B) in the diffe...
<p>Electrophoretic profiles and antibody labelling of PrP<sup>res</sup> as detected by mAbs Sha31 (A...
<p>All mice were inoculated with the same vCJD prion isolate. Immunoblots were analysed by enhanced ...
<p>Labelling for PrP<sup>d</sup> in the brain (indicated by brown staining) from several ruminant sp...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 Mab. Similar quantities of PrP<sup>re...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 and 12B2 mAbs. Similar quantities of ...
<div><p>(A) Primary or secondary (lane 6) transmission to tgBov mice. BSE-type inocula include cattl...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>Histoblots of 4 representative anteroposterior mouse brain sections are shown. Comparison has bee...
<p>Immunoblots of brain PrP<sup>res</sup> detected with SHA 31 mAb. Direct sample and 1/5 dilutions ...
<p>Electrophoretic profiles and antibody labelling of PrP<sup>res</sup> as detected by mAbs Sha31 (A...
<p>PMCA reactions were seeded with BSE brain material (10<sup>−2</sup> dilution) from different spec...
<p>Homogenates were subjected to proteinase K digestion followed by immunoblotting using Sha31 monoc...
<p>Mice were challenged by oral (lane 5–8) or the intra-cerebral route (lanes 1–4). A) Western blot ...
<p>Each lane represents PK-digested PrP<sup>Sc</sup> probed with an anti-PrP monoclonal antibody. Mo...
<p>PrP<sup>res</sup> was detected by western blot using the mAbs Sha31 (A) and 12B2 (B) in the diffe...
<p>Electrophoretic profiles and antibody labelling of PrP<sup>res</sup> as detected by mAbs Sha31 (A...
<p>All mice were inoculated with the same vCJD prion isolate. Immunoblots were analysed by enhanced ...
<p>Labelling for PrP<sup>d</sup> in the brain (indicated by brown staining) from several ruminant sp...