<p>The figures show the change induced by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of the rate of progression, <i>r<sub>P</sub></i>, (x-axes). The right panel shows how treatment frequency increases as a function of the <i>r<sub>P</sub></i>. Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% confidence interval of the mean, inferred through 1000 bootstrap samples.</p
<p>Changes in failure rates associated with either increasing AS/AR IC50 (panels A–B), increasing DH...
<p>n: number of resistance tests (first test/patient per year) presenting with mutations associated ...
<p>The first row of panels shows the results of simulations for the low-risk sub-population where th...
<p>The figures show the change induced by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of th...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> for an asymmetric...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of ...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of ...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> for different rel...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-003...
<p>For each data point, its location on the X axis represents the predicted ratio of incorrect treat...
<p>The schematic on the left illustrates treatment adjustment upon progression. A patient colonized ...
<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-003...
<p>Treatment failure vs. time for the SOCS trial (red), and our simulation thereof (black), shown by...
<p>Changes in failure rates associated with either increasing AS/AR IC50 (panels A–B), increasing DH...
<p>n: number of resistance tests (first test/patient per year) presenting with mutations associated ...
<p>The first row of panels shows the results of simulations for the low-risk sub-population where th...
<p>The figures show the change induced by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of th...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> for an asymmetric...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of ...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> as a function of ...
<p>The figure shows the change conferred by ISS<sub>7</sub> and ISS<sub>Last</sub> for different rel...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
<p>Points correspond to the mean over 10<sup>4</sup> simulations, error-bars correspond to the 95% c...
<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-003...
<p>For each data point, its location on the X axis represents the predicted ratio of incorrect treat...
<p>The schematic on the left illustrates treatment adjustment upon progression. A patient colonized ...
<p>As in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.0030133#pcbi-003...
<p>Treatment failure vs. time for the SOCS trial (red), and our simulation thereof (black), shown by...
<p>Changes in failure rates associated with either increasing AS/AR IC50 (panels A–B), increasing DH...
<p>n: number of resistance tests (first test/patient per year) presenting with mutations associated ...
<p>The first row of panels shows the results of simulations for the low-risk sub-population where th...