Different 5-HT receptors mediate the effect of 5-HT on AP firing in PFC FS interneurons and pyramidal neurons.

<p>A, C, Representative AP recordings showing the effect of 5-HT (20 µM) in the presence of the 5-HT₂ antagonist Ketanserin (10 µM) or the 5-HT₁ antagonist NAN190 (10 µM) in a FS interneuron and a pyramidal neuron. Scale bars: 20 mV, 50 ms. B, D, Cumulative data (mean ± SEM) showing the percentage changes of the firing rate by 5-HT (20 µM) in the presence of different antagonists in FS interneurons and pyramidal neurons.