Association between blood glucose and heparanase levels.

<p><b>A, B</b>. Urine and plasma heparanase levels presented according to gender. Shown are average (±SE) values of heparanase levels in urine (A) and plasma (B) quantified by ELISA in males (M) and females (F) of healthy volunteers (control), T2DM patients and T2DM patients who underwent kidney transplantation. <b>C, D</b>. Association between urine and plasma heparanase and blood glucose levels. Heparanase levels in plasma and urine were correlated with blood glucose levels using the non-parametric Spearman's rank test. Heparanase levels in the urine were found to correlate with blood glucose (<b>C</b>; r = 0.52, p = 0.0001); blood glucose was also associated with plasma heparanase (<b>D</b>; r = 0.38, p = 0.003).