Adult MT4-MMP null have subtle abnormalities in the renal papilla.
- Manakan B. Srichai (356219)
- Heloisa Colleta (356221)
- Leslie Gewin (356222)
- Linsey Matrisian (356224)
- Ty W. Abel (356225)
- Naohiko Koshikawa (141176)
- Motoharu Seiki (141191)
- Ambra Pozzi (317770)
- Raymond C. Harris (356226)
- Roy Zent (317771)
Publication date
February 2013
DOIAbstract
<p>(<b>A–B</b>) No gross abnormalities are seen in low power (50X) images of H and E stained kidneys from MT4-MMP null mice (A) when compared to C57/BL6 controls (B). (<b>C–F</b>) Tubules in the deep papilla of MT4-MMP null kidneys are less tightly packed and show subtle evidence of disorganization (C, E). C–D, H&E, 200X; E–F, PAS, 400X. (<b>G–H</b>) The cortex of MT4-MMP null kidneys appear morphologically normal with no apparent decrease number of glomeruli, PAS, 200X.</p
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