Representative images depicting diffusion and perfusion characteristics of an ischemic rat brain.

<p>Data sets acquired at 1 hour post-transient middle cerebral artery occlusion (tMCAO) includes, (A1) diffusion weighted echo planar image (b = 1000 s/mm²), (A2) Corresponding apparent diffusion co-efficient map, and (A3) T₂-weighted turbo spin echo image. Row (B) represents perfusion echo planar images (PE-EPI) acquired with the parallel imaging reconstruction algorithm (RA), generalized auto-calibrating partially parallel acquisition at acceleration factor (AF) of 4. (B1) PE-EPI acquisition demonstrating altered perfusion characteristics following tMCAO, (B2) derived relative cerebral blood volume (rel-CBV) map and (B3) relative cerebral blood flow (rel-CBF) map. Row (C) represents PE-EPI images acquired with the RA, modified sensitivity encoding at AF 4. (C1) PE-EPI acquisition, (C2) rel-CBV map and (C3) rel-CBF map. Arrow marks on images (B1) and (C1) indicates differential sensitivity to first-pass gadolinium diethylene triaminepentaacetic acid and the arrows on (C2) and (C3) may probably indicate reconstruction related artefacts.