Effect of fluoxetine treatment on behavioral despair in adolescent and adult rats.

<p>Data are presented as mean ± S.E.M. of time spent on immobility (n = 10). 10 Days following chronic fluoxetine treatment (12 mg/kg) behavioral despair, expressed as immobility in the forced swim test, was increased in adolescent, but unaffected in adult rats. ^ap<0.05 main age effect; ^∧p<0.05 age x treatment interaction; ^*p<0.05 fluoxetine <i>versus</i> methylcellulose in age group.