Cell line response to histone deacetylase inhibition.

<p>A) The effect of TSA treatment (250 ng/mL for 16 h) on the expression of <i>CXCL1</i>–<i>3</i>, <i>CXCL8</i> and <i>CXCR1/2</i>. B) Densitometry analysis of expression in treated versus untreated samples when normalised to <i>beta actin</i>. Data is graphed as mean ± standard error of mean (n = 3). C) Treatment with TSA also effects the production of CXCL2 and CXCL8 at protein level in SKMES-1 cells. Chemokines were quantified in conditioned media removed from culture after exposure to TSA (250 ng/mL for 16 h). Data is graphed as mean ± standard error of mean (n = 3). (UT – untreated, TSA – Trichostatin A).